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Game theory provides an alternative to conventional decision making processes that allows us to reason about the responses of intelligent adversaries to security policies and resource allocations. Game-theoretic models can leverage the understanding that law enforcement officials have of adversary capabilities, goals, and historical patterns to improve decisions in complex homeland security and policing environments and to effectively predict and react to the behavior of adversaries in different situations. The focus of the symposium will be on introducing the fundamental principles of these technologies, and providing examples where we bridge the gap between theoretical research and real-world practitioners.